alzheimers news-i would do it

ALZHEIMERS NEWS-i WOULD DO  IT

in his blog dr daniel gibbs wrote about this interesting study described below
could this be a new treatment or preventative treatment for alzheimers disease

the apoe gene controls lipid transport in the brain

if you have the apoe2 gene you are somewhat protected from getting late onset alzheimers
if you have the apoe3 gene you are less protected than if you have apoe2
if you have the apoe4 gene you are at increased risk of getting late onset alzheimers
if you have the apoe4 apoe4 gene you have an 15 times increased chance of getting the disease

we all have two genes
the best to have is apoe2 apoe2
the worst to have is apoe4 apoe4
in the middle is apoe3 apoe3

i like dr gibbs have the apoe4 apoe4 gene
i have mild cognitive impairment due to alzheimers 
he now has progressed to mild alzheimers
i have not so far

he had a large brain bleed when he took aduhelm
luckily i did not have a brain bleed or brain edema when i took it

aduhelm leqembi and kisunia can cause brain bleeds in apoe4 patients
i got the benefit of 34 months of aduhelm
he only got a few doses before he bled

whats next
maybe this

with alzheimers
amyloid accumulates in the brain to form amyloid plaques
later tau protein unwinds to form tau tangles
the amyloid can be measured  in the spinal fluid and in the blood and on amyloid pet scans
the tau can be measured in the spinal fluid and in the blood and on tau pet scans

what if you could add the apoe2 gene to a person with apoe4 apoe4

would it make a difference in amyloid and tau levels and would it make a difference in a persons memory decline

they now have gene treatments for hemophilia so that the normal gene is given to a person with hemophilia and they have normal clotting studies for years
otherwise they have to get monthly infusions of clotting factors to stay alive
the cost of the gene treatment is 3.5 million dollars

there is a treatment for sickle cell anemia where the gene for normal hemoglobulin takes over to produce normal hemoglobulin 
sickle cell is a debilitating disease sometimes fatal secondary to strokes heart attacks or infection

so what if we could do something like that with alzheimers disease
maybe like change the apoe4 to apoe2

so in a study this company posted the results of just that

they took a virus that didnt cause health problems and loaded the apoe2 gene on the virus then injected that into the spinal fluid of patients with the apoe4 apoe4 gene

they found that the amyloid levels stabilized the tau levels declined and the memory stabilized
the person who had the more advanced alzheimers did the best

they also are doing the same thing with a mutated apoe4 called christchurch
this was taken from a lady from columbia who had the early onset alzheimers gene which causes you to develop alzheimers at a young age like 40-50
she didnt get it 
they discovered the christchurch apoe4 gene which was protecting her

now they making the christchurch apoe4 gene to attach to a virus to be injected into the spinal fluid
hopefully it will cause the same good results as it did in the columbian lady

this may work
they re planning larger clinical trials to see if it works
if it does this may be a way to slow this down or prevent it in those of us who have the apoe4 apoe4 gene

would i participate in the clinical trial
absolutely i would

would i consider being treated with this if it makes it to market
absolutely

the question is 
how much will it cost
a million 2 million 3 million

can we afford it
can i afford it

would i
i would

the organicgreen doctor