welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, November 8, 2024

alzheimers news-i will do it

ALZHEIMERS NEWS-I WILL DO IT

that is me speaking last year at the walk to end alzheimers 
in four years i want to be able to vote again and be able to know that i voted again
i want to be able if asked to speak at the 2028 walk to end alzheimers

to do this
i have to
maintain my healthy living like i have been doing
continue taking my aricept or donepezil to slow down symptoms
then
look for other things that may come available to slow down this disease

i may have found one
maybe

in 2016 i had an amyloid pet scan that was positive for amyloid plaques in my brain
this is the hallmark of alzheimers disease
if you have alzheimers you will have a positive amyloid pet scan

i was accepted in the biogen aduhelm or aducanumab treatment study in 2016

i started infusions for 18 months that turned out to be placebo
the study was delayed twice once by the pandemic and once by problems with the study 
it was eventually restarted and i received 34 months of aduhelm infusions

in the fall of 2023 my last amyloid pet scan was negative for amyloid plaque

in February of 2024 i had a final interview and studies for the biogen aduhelm study 

so the goal was to remove the amyloid plaque
it aduhelm did its job

these drugs called moncolonal amyloid antibodies slow down memory decline by about 25-30%

my drug aduhelm was removed from the market in favor of its sister drug leqembi which showed slightly better results and had all its initial clinical trials completed 

so leqembi is approved for use in mild cognitive impairment due to alzheimers and for early alzheimers
the sooner you take it the better it works
another similar drug kisunia also was approved

now here i am 1 year after having all the amyloid plaque removed from my brain
what do i do now
wait

well no i dont l like to wait

so enter this thing below

this is the leqembi auto injector
it probably will be approved by the fda for administering leqembi

when i got my infusions it was a 3 hr drive to ucla and a 3 hr drive home
a visit to see the neurologist to approve the infusion
a wait for the meds to be mixed up by the pharmacist 
an hour infusion time to get the meds
total time 9 hours

enter auto injector
time involved 
15 secs to inject
done

if the autoinjector is approved by the fda then folks ie me can give it myself at home eventually

they are seeking approval by the fda for leqembi to be given as a maintenance injection once a week to keep the amyloid plaque from reaccumulating

i am anxiously waiting its approval

here is a review article about this from alzheimers weekly

my thoughts
ill definitely do it

if you are in the santa barbara area join us for our walk to end alzheimers at the link below
or
join a walk where you live
here is the link to our team organicgreendoctor to join or donate 
see you on saturday november 16th at chase palm park

the organicgreen doctor

3 comments:

  1. Is leqembi covered by insurance?

    ReplyDelete
  2. yes it its covered by medicare but not private insurance
    you have to be diagnosed with mild cognitive impairment due to alzheimers or early alzheimers
    you have to have an mri and an amyloid pet scan or a spinal tap for amyloid and tau
    you also have to have the apoe 4 gene test to see if you are apoe 4 apoe 4 which puts you at an increased risk for brain bleeds
    i am apoe 4 apoe 4 positive but did not have any brain swelling or bleeds when i took the aduhelm the cousin to leqembi
    togd

    ReplyDelete