alzheimers news-round three

ALZHEIMERS NEWS-ROUND THREE

the name of the study is
the aducanumab study
sponsored by biogen

this is the study that alzheimers folks are keeping
their eye on

it could be the one
we are waiting for

i sure hope so

the bad beta amyloid that is
thought to be the cause of alzheimers disease
accumulates in the brain causing brain cell destruction
ie
alzheimers disease

stop this accumulation you might stop alzheimers disease
or at least slow it down

so they isolated this antibody to the bad beta amyloid
from old folks who for some
reason didnt get alzheimers disease

this antibody was named
aducanumab

it goes into the brain when given as an infusion
binds to the bad beta amyloid and removes it

it also removes the plaques that form in the brain


nature.com

here on the left are beta amyloid scans called amyvid scans
done on folks before the study started
all that red stuff is beta amyloid accumulation
then
on the right are the same folks scans after receiving
the infusions of aducanumab after several weeks

you can see the 10 mgm dose completely cleared the amyloid

only the folks who got the placebo
the fake stuff
didnt change

this removal of the amyloid also correlated with
an improvement in memory

these scans are from the small initial phase 1 study

now i am applying to get into the big phase 3 study that is being
done on several hundred folks

if i get in
if i get the real stuff and not the placebo
my scans should go from abnormal to normal looking
in just a few weeks
my alzheimers will be delayed or stopped in its tracks

this is why we are so excited about this study

so today
its round three
we make the 300 mile journey
to the ut southwestern alzheimers center in dallas
to have
several memory tests
and
the baseline mri

if i pass these tests
ie
my memory is still off
my mri shows nothing bad like stroke tumor masses etc
then i will have an amyvid pet scan soon like those above

if the amyvid scan is positive
then im in the study
that means i have alzheimers disease as sure as you can be

then
i will start the infusions

this all has to happen in the next 2 weeks

lets just say we are excited today

the organicgreen doctor