gene

GENE

one of my best friends name is gene
one of those forever friends
i could write a lot about him and things we did
but then he would have to write about things i did
then i would write about things he did
then
well you can see where thats going
nothing good might come of that
so

im writing about another gene
thats the apoe4 gene and i guess this all could apply to
other genes like eg huntingtons disease

first the apoe4 gene
if you have a double version or
a homozygous version ie the apoe4/apoe4 version
you have an increased chance of developing alzheimers
disease
a 30 times chance of developing the disease the late onset
version of alzheimers disease
10% of us have this combo
up to 60% of you have the singe version of apoe4

so theres a lot of you 6 of the 10 of you who read this have
this apoe4 gene
fairly common gene wouldnt you say

some of you with the apoe4/apoe4 gene will not get alzheimers

so its not one of those 100% genes
like huntingtons disease
like the dominant genes for alzheimers that some get
you get the gene you get the disease
100% guaranteed
(see the colombian alzheimers study)

with eg cystic fibrosis if both parents have a cystic fibrosis gene
then the child has a 25% chance of getting the gene
if the child gets the double gene they have a 100% chance of getting the disease
1 in 30 white folks carry this gene

with the apoe4 gene the double gene apoe4/apoe4 you have a
30% chance of maybe getting late onset alzheimers disease

why am i writing about this

i had a lengthy conversation with someone a young someone in
their thirties who got tested you know those things you see on tv
where they swab your cheek and its sent in and then
back comes results that has no real good accompanying explanation
of what that means what it really really means for that particular person

i felt ready when i was tested
i was mentally ready to be tested
i was 60 and had just been told i had mild cognitive impairment amnestic
type that could turn out to be alzhiemers disease
based on changes on mental status evaluation over a 3-5 year time period
things i had noticed in my daily life
a strong strong family history of alzheimers disease
so i wanted as much information as possible to help me make decisions
on my personal situation moving forward

i was ready so i was tested
it was though one of those surreal moments when i opened that
letter and read the results
even then i didnt understand what it really all meant like i do now

positive test with the history above is not a good thing

now move to this person i had the talk with

thirty some family history in grandparents and uncles
now i was tested by a real reputable lab that my neurologists used
this person was tested by that lab that advertises on tv that the fda
is trying to shut down

but i dont doubt though that this persons apoe4 test wasnt correct
what was missing was what does it really really mean
the lab where i was tested will not test cause you want it tested
it has to be ordered by someone who feels its necessary and can
appropriately counsel you on what it really really means

so what does this mean for this thirty year old
it means that this person has a 70% chance that this person will not get
alzheimers disease
but im sure this person is locked in on the 30% risk the person was given

the odds are
1 in 1 you will die of something
1 in 7 you will die of heart disease
1in 7 cancer
1 in 28 chronic lower respiratory disease
1 in 108 moving vehicle accident
1 in 340 assault by firearm

1 in 5 is the lifetime risk of developing alzheimers disease in women
1 in 10 for men
(women live much longer than men so they are more likely to get it)

so in summary for this person
i wouldnt have been tested without counseling first
this person could have a 1 in 5 chance of getting alzheimers without the
apoe4 gene
the apoe4/apoe4 gene increases this some
that xx gene a female has increases the chance almost as much as the apoe4 gene

there are so many things that factor in to someone getting this disease
it appears that for the apoe4/apoe4 gene combo it may not be
as important eg as

controlling ones blood pressure
cholesterol
diabetes
weight
getting exercise
not smoking
having moderate alcohol intake
sleeping normal
controlling anxiety and depression
being happy
staying mentally active
eating a mediterranean diet of less red meat  eat fish fruits nuts veggies
olive oil and whole cereal foods

so be careful of being tested for these different diseases
make sure you are ready if you are going to be tested
make sure you get the appropriate counseling
if you are positive for things like huntingtons or the dominant gene
for alzheimers eg
make sure you have your life planned out
with life insurance disability insruance and maybe long term care insurance
thanks to obamacare health insurance wont be an issue

you wont be able to get any of these after these diagnoses are on
your official medical records
that includes the apoe4/apoe4 gene results

so testing for those gene things should  not be taken lightly
do genetic counseling first
so
the only gene i want to have to be associated with in the future
is my old friend
gene

the organicgreen doctor