organicgreendoctor: alzheimers news-will this work maybe

organicgreendoctor: alzheimers news-will this work maybe: ALZHEIMERS NEWS-WILL THIS WORK MAYBE there is late onset alzheimers disease thats what i have  it can be caused by the apoe4 gene especially...

alzheimers news-will this work maybe

ALZHEIMERS NEWS-WILL THIS WORK MAYBE

there is late onset alzheimers disease
thats what i have 
it can be caused by the apoe4 gene especially if you get the homozygous or apoe4/apoe4 version
your risks are increased of getting alzheimers by 10-20 times
you can counterbalance the effects of the apoe4 gene by aggressively pursuing a healthy life style 

there is early onset alzheimers 
it can be caused by a dominant gene such that if you get this gene you will get alzheimers at an early age like 40s-50s

there is nothing you can do to stop the early onset gene
if you have the gene then you will get alzheimers at an early age

in the theory of alzheimers it is thought this amyloid plaques accumulates which kill brain cells then as these cells die tau proteins inside brain cells unravel and form tau tangles which kills more brain cells then inflammation sets it to kill more brain cells
thats what happens as the disease progress

some think that if you could remove those amyloid plaques or keep them from forming then alzheimers could be slowed down

new drugs called antiamyloid monoclonal antibodies were developed that will bind amyloid and or amyloid plaques and remove them from the brain

the first to get approved was my drug aduhelm or aducanumab
it worked to remove the amyloid plaque
it was taken off the market since it didnt work as well as the new drugs leqembi and kisunia
both of which are available for use in mild cognitive impairment due to alzheimers and mild alzheimers disease

patients with early onset alzheimers who had the early genes like presenilin took these drugs and they didnt work

one of the early drugs they used was gantenerumab
in this study linked here and here these patients who had no symptoms were followed for 8 years
they all should have developed alzheimers symptoms
only 50% of them developed symptoms and 50% had no symptoms develop
it should have been 100% developed symptoms

this implies that the antiamyloid drug seems to be slowing down the disease symptoms

the plan now is to extend this longer using maybe leqembi since its approved and is available for use

there has been nothing thats ever worked in these genetic early onset alzheimers patients
nothing to slow down symptoms

the secret may be treating them months to years before symptoms start

then
will this then transfer to late onset alzheimers disease like i have

will treating these prealzheimers patients months or years before symptoms starts
will that delay and slow down symptoms
maybe

i feel like i was accidently diagnosed early so maybe this will help me 

i am watching closely studies using leqembi as a maintenance drug after you are initially treated for the 1 year to remove the amyloid plaques

for me 
i have mild cognitive impairment due to alzheimers
i had my amyloid plaques removed with the aduhelm infusions

would taking leqembi monthly infusions as maintenance dosing prevent the plaques from reaccumulating
will that make a difference in slowing down this disease

It might
it may be the only option i have to do more than i have done to slow this all down
the other drugs in clinical trials probably wont get on the market in time to help me

i dont qualify for these new drug clinical trials as you have to have a positive amyloid pet scan to enter the studies
mine are now negative

a conundrum

the organicgreen doctor

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